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- Title
Asc1 supports cell-wall integrity near bud sites by a Pkc1 independent mechanism.
- Authors
Melamed, Daniel; Bar-Ziv, Lavi; Truzman, Yossi; Arava, Yoav
- Abstract
The yeast ribosomal protein Asc1 is a WD-protein family member. Its mammalian ortholog, RACK1 was initially discovered as a receptor for activated protein C kinase (PKC) that functions to maintain the active conformation of PKC and to support its movement to target sites. In the budding yeast though, a connection between Asc1p and the PKC signaling pathway has never been reported.
- Publication
PloS one, 2010, Vol 5, Issue 6, pe11389
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0011389