We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Disrupted functional connectivity with dopaminergic midbrain in cocaine abusers.
- Authors
Tomasi, Dardo; Volkow, Nora D; Wang, Ruiliang; Carrillo, Jean H; Maloney, Thomas; Alia-Klein, Nelly; Woicik, Patricia A; Telang, Frank; Goldstein, Rita Z
- Abstract
Chronic cocaine use is associated with disrupted dopaminergic neurotransmission but how this disruption affects overall brain function (other than reward/motivation) is yet to be fully investigated. Here we test the hypothesis that cocaine addicted subjects will have disrupted functional connectivity between the midbrain (where dopamine neurons are located) and cortical and subcortical brain regions during the performance of a sustained attention task.
- Publication
PloS one, 2010, Vol 5, Issue 5, pe10815
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0010815