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- Title
Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers.
- Authors
Liao, Jian-You; Ma, Li-Ming; Guo, Yan-Hua; Zhang, Yu-Chan; Zhou, Hui; Shao, Peng; Chen, Yue-Qin; Qu, Liang-Hu
- Abstract
MicroRNAs (miRNAs) are approximately 22-nt small non-coding regulatory RNAs that have generally been considered to regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent studies have reported that some miRNAs localize to and function in the nucleus.
- Publication
PloS one, 2010, Vol 5, Issue 5, pe10563
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0010563