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- Title
Analysis of multiple sarcoma expression datasets: implications for classification, oncogenic pathway activation and chemotherapy resistance.
- Authors
Konstantinopoulos, Panagiotis A; Fountzilas, Elena; Goldsmith, Jeffrey D; Bhasin, Manoj; Pillay, Kamana; Francoeur, Nancy; Libermann, Towia A; Gebhardt, Mark C; Spentzos, Dimitrios
- Abstract
Diagnosis of soft tissue sarcomas (STS) is challenging. Many remain unclassified (not-otherwise-specified, NOS) or grouped in controversial categories such as malignant fibrous histiocytoma (MFH), with unclear therapeutic value. We analyzed several independent microarray datasets, to identify a predictor, use it to classify unclassifiable sarcomas, and assess oncogenic pathway activation and chemotherapy response.
- Publication
PloS one, 2010, Vol 5, Issue 4, pe9747
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0009747