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- Title
Characterization of the Melanoma miRNAome by Deep Sequencing.
- Authors
Stark, Mitchell S; Tyagi, Sonika; Nancarrow, Derek J; Boyle, Glen M; Cook, Anthony L; Whiteman, David C; Parsons, Peter G; Schmidt, Christopher; Sturm, Richard A; Hayward, Nicholas K
- Abstract
MicroRNAs (miRNAs) are 18-23 nucleotide non-coding RNAs that regulate gene expression in a sequence specific manner. Little is known about the repertoire and function of miRNAs in melanoma or the melanocytic lineage. We therefore undertook a comprehensive analysis of the miRNAome in a diverse range of pigment cells including: melanoblasts, melanocytes, congenital nevocytes, acral, mucosal, cutaneous and uveal melanoma cells.
- Publication
PloS one, 2010, Vol 5, Issue 3, pe9685
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0009685