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- Title
Automated network analysis identifies core pathways in glioblastoma.
- Authors
Cerami, Ethan; Demir, Emek; Schultz, Nikolaus; Taylor, Barry S; Sander, Chris
- Abstract
Glioblastoma multiforme (GBM) is the most common and aggressive type of brain tumor in humans and the first cancer with comprehensive genomic profiles mapped by The Cancer Genome Atlas (TCGA) project. A central challenge in large-scale genome projects, such as the TCGA GBM project, is the ability to distinguish cancer-causing "driver" mutations from passively selected "passenger" mutations.
- Publication
PloS one, 2010, Vol 5, Issue 2, pe8918
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0008918