We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells.
- Authors
Vrba, Lukas; Jensen, Taylor J; Garbe, James C; Heimark, Ronald L; Cress, Anne E; Dickinson, Sally; Stampfer, Martha R; Futscher, Bernard W
- Abstract
The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood.
- Publication
PloS one, 2010, Vol 5, Issue 1, pe8697
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0008697