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Title
Dynamic near-infrared optical imaging of 2-deoxyglucose uptake by intracranial glioma of athymic mice.
Authors
Zhou, Heling; Luby-Phelps, Kate; Mickey, Bruce E; Habib, Amyn A; Mason, Ralph P; Zhao, Dawen
Abstract
It is recognized that cancer cells exhibit highly elevated glucose metabolism compared to non-tumor cells. We have applied in vivo optical imaging to study dynamic uptake of a near-infrared dye-labeled glucose analogue, 2-deoxyglucose (2-DG) by orthotopic glioma in a mouse model.