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- Title
Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples.
- Abstract
The article presents a study related to the profiling of critical cancer gene mutations in clinical tumor samples. An optimized mutation profiling platform was developed and implemented, in order to interrogate 400 mutations in 33 known oncogenes and tumor suppressors. The results indicate that the clinical feasibility of high-throughput mutation profiling to query a large panel of 'actionable' cancer gene mutations. The background, methodology, and conclusions, of the study, are discussed in detail.
- Publication
PLoS ONE, 2009, Vol 4, Issue 11, p1
- ISSN
1932-6203
- Publication type
Academic Journal
- DOI
10.1371/journal.pone.0007887