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- Title
Periconceptional Maternal Folic Acid Use of 400 μg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child.
- Abstract
The article discusses a study conducted to investigate whether periconceptional maternal folic acid use and markers of global DNA methylation affect methylation of the Insulin-Like Growth Factor 2 Gene Differentially Methylation Region (IGF2 DMR) in a child. It has been stated that the study also tested whether methylation of the IGF2 DMR was independently associated with birth weight. It has been stated that the study results found that periconceptional folic acid use is associated with epigenetic changes in IGF2 in the child that may affect growth and development of the child.
- Publication
PLoS ONE, 2009, Vol 4, Issue 11, p1
- ISSN
1932-6203
- Publication type
Academic Journal
- DOI
10.1371/journal.pone.0007845