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- Title
Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium.
- Authors
Charles, Richelle C; Harris, Jason B; Chase, Michael R; Lebrun, Lauren M; Sheikh, Alaullah; LaRocque, Regina C; Logvinenko, Tanya; Rollins, Sean M; Tarique, Abdullah; Hohmann, Elizabeth L; Rosenberg, Ian; Krastins, Bryan; Sarracino, David A; Qadri, Firdausi; Calderwood, Stephen B; Ryan, Edward T
- Abstract
S. Typhi, a human-restricted Salmonella enterica serovar, causes a systemic intracellular infection in humans (typhoid fever). In comparison, S. Typhimurium causes gastroenteritis in humans, but causes a systemic typhoidal illness in mice. The PhoP regulon is a well studied two component (PhoP/Q) coordinately regulated network of genes whose expression is required for intracellular survival of S. enterica.
- Publication
PloS one, 2009, Vol 4, Issue 9, pe6994
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0006994