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- Title
Evidence for limited genetic compartmentalization of HIV-1 between lung and blood.
- Authors
Heath, Laura; Fox, Alan; McClure, Jan; Diem, Kurt; van 't Wout, Angélique B; Zhao, Hong; Park, David R; Schouten, Jeffrey T; Twigg, Homer L; Corey, Lawrence; Mullins, James I; Mittler, John E
- Abstract
HIV-1 is frequently detected in the lungs of infected individuals and is likely important in the development of pulmonary opportunistic infections. The unique environment of the lung, rich in alveolar macrophages and with specialized local immune responses, may contribute to differential evolution or selection of HIV-1.
- Publication
PloS one, 2009, Vol 4, Issue 9, pe6949
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0006949