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- Title
Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods.
- Authors
Elobeid, Mai A; Padilla, Miguel A; McVie, Theresa; Thomas, Olivia; Brock, David W; Musser, Bret; Lu, Kaifeng; Coffey, Christopher S; Desmond, Renee A; St-Onge, Marie-Pierre; Gadde, Kishore M; Heymsfield, Steven B; Allison, David B
- Abstract
Dropouts and missing data are nearly-ubiquitous in obesity randomized controlled trails, threatening validity and generalizability of conclusions. Herein, we meta-analytically evaluate the extent of missing data, the frequency with which various analytic methods are employed to accommodate dropouts, and the performance of multiple statistical methods.
- Publication
PloS one, 2009, Vol 4, Issue 8, pe6624
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0006624