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- Title
Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria.
- Authors
Kaur, Devinder; Pham, Ha; Larrouy-Maumus, Gérald; Rivière, Michel; Vissa, Varalakshmi; Guerin, Marcelo E; Puzo, Germain; Brennan, Patrick J; Jackson, Mary
- Abstract
Mycobacteria produce two unique families of cytoplasmic polymethylated polysaccharides -- the methylglucose lipopolysaccharides (MGLPs) and the methylmannose polysaccharides (MMPs) -- the physiological functions of which are still poorly defined. Towards defining the roles of these polysaccharides in mycobacterial physiology, we generated knock-out mutations of genes in their putative biosynthetic pathways.
- Publication
PloS one, 2009, Vol 4, Issue 5, pe5447
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0005447