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- Title
Paradox of vaccination: is vaccination really effective against avian flu epidemics?
- Authors
Iwami, Shingo; Suzuki, Takafumi; Takeuchi, Yasuhiro
- Abstract
Although vaccination can be a useful tool for control of avian influenza epidemics, it might engender emergence of a vaccine-resistant strain. Field and experimental studies show that some avian influenza strains acquire resistance ability against vaccination. We investigated, in the context of the emergence of a vaccine-resistant strain, whether a vaccination program can prevent the spread of infectious disease. We also investigated how losses from immunization by vaccination imposed by the resistant strain affect the spread of the disease.
- Publication
PloS one, 2009, Vol 4, Issue 3, pe4915
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0004915