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Title
A beta-catenin-dependent Wnt pathway mediates anteroposterior axon guidance in C. elegans motor neurons.
Authors
Maro, Géraldine S; Klassen, Matthew P; Shen, Kang
Abstract
Wnts are secreted glycoproteins that regulate diverse aspects of development, including cell proliferation, cell fate specification and differentiation. More recently, Wnts have been shown to direct axon guidance in vertebrates, flies and worms. However, little is known about the intracellular signaling pathways downstream of Wnts in axon guidance.