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- Title
Sleep restriction increases the risk of developing cardiovascular diseases by augmenting proinflammatory responses through IL-17 and CRP.
- Authors
van Leeuwen, Wessel M A; Lehto, Maili; Karisola, Piia; Lindholm, Harri; Luukkonen, Ritva; Sallinen, Mikael; Härmä, Mikko; Porkka-Heiskanen, Tarja; Alenius, Harri
- Abstract
Sleep restriction, leading to deprivation of sleep, is common in modern 24-h societies and is associated with the development of health problems including cardiovascular diseases. Our objective was to investigate the immunological effects of prolonged sleep restriction and subsequent recovery sleep, by simulating a working week and following recovery weekend in a laboratory environment.
- Publication
PloS one, 2009, Vol 4, Issue 2, pe4589
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0004589