We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A late role for bmp2b in the morphogenesis of semicircular canal ducts in the zebrafish inner ear.
- Authors
Hammond, Katherine L; Loynes, Helen E; Mowbray, Catriona; Runke, Greg; Hammerschmidt, Matthias; Mullins, Mary C; Hildreth, Victoria; Chaudhry, Bill; Whitfield, Tanya T
- Abstract
The Bone Morphogenetic Protein (BMP) genes bmp2 and bmp4 are expressed in highly conserved patterns in the developing vertebrate inner ear. It has, however, proved difficult to elucidate the function of BMPs during ear development as mutations in these genes cause early embryonic lethality. Previous studies using conditional approaches in mouse and chicken have shown that Bmp4 has a role in semicircular canal and crista development, but there is currently no direct evidence for the role of Bmp2 in the developing inner ear.
- Publication
PloS one, 2009, Vol 4, Issue 2, pe4368
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0004368