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Title
Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
Authors
Mabilleau, Guillaume; Sabokbar, Afsie
Abstract
Interleukin-32 (IL-32) is a newly described cytokine produced after stimulation by IL-2 or IL-18 and IFN-gamma. IL-32 has the typical properties of a pro-inflammatory mediator and although its role in rheumatoid arthritis has been recently reported its effect on the osteoclastogenesis process remains unclear.