We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Human gene coexpression landscape: confident network derived from tissue transcriptomic profiles.
- Authors
Prieto, Carlos; Risueño, Alberto; Fontanillo, Celia; De las Rivas, Javier
- Abstract
Analysis of gene expression data using genome-wide microarrays is a technique often used in genomic studies to find coexpression patterns and locate groups of co-transcribed genes. However, most studies done at global "omic" scale are not focused on human samples and when they correspond to human very often include heterogeneous datasets, mixing normal with disease-altered samples. Moreover, the technical noise present in genome-wide expression microarrays is another well reported problem that many times is not addressed with robust statistical methods, and the estimation of errors in the data is not provided.
- Publication
PloS one, 2008, Vol 3, Issue 12, pe3911
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0003911