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- Title
Prefrontal cortex glutamate correlates with mental perspective-taking.
- Authors
Montag, Christiane; Schubert, Florian; Heinz, Andreas; Gallinat, Jürgen
- Abstract
Dysfunctions in theory of mind and empathic abilities have been suggested as core symptoms in major psychiatric disorders including schizophrenia and autism. Since self monitoring, perspective taking and empathy have been linked to prefrontal (PFC) and anterior cingulate cortex (ACC) function, neurotransmitter variations in these areas may account for normal and pathological variations of these functions. Converging evidence indicates an essential role of glutamatergic neurotransmission in psychiatric diseases with pronounced deficits in empathy. However, the role of the glutamate system for different dimensions of empathy has not been investigated so far.
- Publication
PloS one, 2008, Vol 3, Issue 12, pe3890
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0003890