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- Title
Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks.
- Authors
Iliopoulos, Dimitrios; Malizos, Konstantinos N; Oikonomou, Pagona; Tsezou, Aspasia
- Abstract
Osteoarthritis is a multifactorial disease characterized by destruction of the articular cartilage due to genetic, mechanical and environmental components affecting more than 100 million individuals all over the world. Despite the high prevalence of the disease, the absence of large-scale molecular studies limits our ability to understand the molecular pathobiology of osteoathritis and identify targets for drug development.
- Publication
PloS one, 2008, Vol 3, Issue 11, pe3740
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0003740