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- Title
Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate.
- Authors
Traka, Maria; Gasper, Amy V; Melchini, Antonietta; Bacon, James R; Needs, Paul W; Frost, Victoria; Chantry, Andrew; Jones, Alexandra M E; Ortori, Catharine A; Barrett, David A; Ball, Richard Y; Mills, Robert D; Mithen, Richard F
- Abstract
Epidemiological studies suggest that people who consume more than one portion of cruciferous vegetables per week are at lower risk of both the incidence of prostate cancer and of developing aggressive prostate cancer but there is little understanding of the underlying mechanisms. In this study, we quantify and interpret changes in global gene expression patterns in the human prostate gland before, during and after a 12 month broccoli-rich diet.
- Publication
PloS one, 2008, Vol 3, Issue 7, pe2568
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0002568