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- Title
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation.
- Authors
Huurman, Volkert A L; Hilbrands, Robert; Pinkse, Gabriëlle G M; Gillard, Pieter; Duinkerken, Gaby; van de Linde, Pieter; van der Meer-Prins, Petronella M W; Versteeg-van der Voort Maarschalk, Minke F J; Verbeeck, Koen; Alizadeh, Behrooz Z; Mathieu, Chantal; Gorus, Frans K; Roelen, Dave L; Claas, Frans H J; Keymeulen, Bart; Pipeleers, Daniel G; Roep, Bart O
- Abstract
Islet cell transplantation can cure type 1 diabetes (T1D), but only a minority of recipients remains insulin-independent in the following years. We tested the hypothesis that allograft rejection and recurrent autoimmunity contribute to this progressive loss of islet allograft function.
- Publication
PloS one, 2008, Vol 3, Issue 6, pe2435
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0002435