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- Title
Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays.
- Authors
Soreq, Lilach; Gilboa-Geffen, Adi; Berrih-Aknin, Sonia; Lacoste, Paul; Darvasi, Ariel; Soreq, Eyal; Bergman, Hagai; Soreq, Hermona
- Abstract
The vast majority of human genes (>70%) are alternatively spliced. Although alternative pre-mRNA processing is modified in multiple tumors, alternative hyper-splicing signatures specific to particular tumor types are still lacking. Here, we report the use of Affymetrix Human Exon Arrays to spot hyper-splicing events characteristic of myasthenia gravis (MG)-thymoma, thymic tumors which develop in patients with MG and discriminate them from colon cancer changes.
- Publication
PloS one, 2008, Vol 3, Issue 6, pe2392
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0002392