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- Title
Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial.
- Authors
Harms, Hendrik; Prass, Konstantin; Meisel, Christian; Klehmet, Juliane; Rogge, Witold; Drenckhahn, Christoph; Göhler, Jos; Bereswill, Stefan; Göbel, Ulf; Wernecke, Klaus Dieter; Wolf, Tilo; Arnold, Guy; Halle, Elke; Volk, Hans-Dieter; Dirnagl, Ulrich; Meisel, Andreas
- Abstract
Pneumonia is a major risk factor of death after acute stroke. In a mouse model, preventive antibacterial therapy with moxifloxacin not only prevents the development of post-stroke infections, it also reduces mortality, and improves neurological outcome significantly. In this study we investigate whether this approach is effective in stroke patients.
- Publication
PloS one, 2008, Vol 3, Issue 5, pe2158
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0002158