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- Title
Characterization of clinically-attenuated Burkholderia mallei by whole genome sequencing: candidate strain for exclusion from Select Agent lists.
- Authors
Schutzer, Steven E; Schlater, Linda R K; Ronning, Catherine M; DeShazer, David; Luft, Benjamin J; Dunn, John J; Ravel, Jacques; Fraser-Liggett, Claire M; Nierman, William C
- Abstract
Burkholderia mallei is an understudied biothreat agent responsible for glanders which can be lethal in humans and animals. Research with this pathogen has been hampered in part by constraints of Select Agent regulations for safety reasons. Whole genomic sequencing (WGS) is an apt approach to characterize newly discovered or poorly understood microbial pathogens.
- Publication
PloS one, 2008, Vol 3, Issue 4, pe2058
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0002058