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- Title
Cross-clade protective immune responses to influenza viruses with H5N1 HA and NA elicited by an influenza virus-like particle.
- Authors
Bright, Rick A; Carter, Donald M; Crevar, Corey J; Toapanta, Franklin R; Steckbeck, Jonathan D; Cole, Kelly S; Kumar, Niranjan M; Pushko, Peter; Smith, Gale; Tumpey, Terrence M; Ross, Ted M
- Abstract
Vaccination is a cost-effective counter-measure to the threat of seasonal or pandemic outbreaks of influenza. To address the need for improved influenza vaccines and alternatives to egg-based manufacturing, we have engineered an influenza virus-like particle (VLP) as a new generation of non-egg or non-mammalian cell culture-based candidate vaccine.
- Publication
PloS one, 2008, Vol 3, Issue 1, pe1501
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0001501