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- Title
A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children.
- Authors
Sokhna, Cheikh; Cissé, Badara; Bâ, El Hadj; Milligan, Paul; Hallett, Rachel; Sutherland, Colin; Gaye, Oumar; Boulanger, Denis; Simondon, Kirsten; Simondon, François; Targett, Geoffrey; Lines, Jo; Greenwood, Brian; Trape, Jean-François
- Abstract
In the Sahel, most malaria deaths occur among children 1-4 years old during a short transmission season. A trial of seasonal intermittent preventive treatment (IPT) with sulfadoxine-pyrimethamine (SP) and a single dose of artesunate (AS) showed an 86% reduction in the incidence of malaria in Senegal but this may not be the optimum regimen. We compared this regimen with three alternatives.
- Publication
PloS one, 2008, Vol 3, Issue 1, pe1471
- ISSN
1932-6203
- Publication type
Journal Article
- DOI
10.1371/journal.pone.0001471