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- Title
Anopheles gambiae antiviral immune response to systemic O'nyong-nyong infection.
- Authors
Waldock, Joanna; Olson, Kenneth E; Christophides, George K
- Abstract
Mosquito-borne viral diseases cause significant burden in much of the developing world. Although host-virus interactions have been studied extensively in the vertebrate host, little is known about mosquito responses to viral infection. In contrast to mosquitoes of the Aedes and Culex genera, Anopheles gambiae, the principal vector of human malaria, naturally transmits very few arboviruses, the most important of which is O'nyong-nyong virus (ONNV). Here we have investigated the A. gambiae immune response to systemic ONNV infection using forward and reverse genetic approaches.
- Publication
PLoS neglected tropical diseases, 2012, Vol 6, Issue 3, pe1565
- ISSN
1935-2735
- Publication type
Journal Article
- DOI
10.1371/journal.pntd.0001565