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- Title
Real-time PCR demonstrates Ancylostoma duodenale is a key factor in the etiology of severe anemia and iron deficiency in Malawian pre-school children.
- Authors
Jonker, Femkje A M; Calis, Job C J; Phiri, Kamija; Brienen, Eric A T; Khoffi, Harriet; Brabin, Bernard J; Verweij, Jaco J; van Hensbroek, Michael Boele; van Lieshout, Lisette
- Abstract
Hookworm infections are an important cause of (severe) anemia and iron deficiency in children in the tropics. Type of hookworm species (Ancylostoma duodenale or Necator americanus) and infection load are considered associated with disease burden, although these parameters are rarely assessed due to limitations of currently used diagnostic methods. Using multiplex real-time PCR, we evaluated hookworm species-specific prevalence, infection load and their contribution towards severe anemia and iron deficiency in pre-school children in Malawi.
- Publication
PLoS neglected tropical diseases, 2012, Vol 6, Issue 3, pe1555
- ISSN
1935-2735
- Publication type
Journal Article
- DOI
10.1371/journal.pntd.0001555