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- Title
Phase II evaluation of sensitivity and specificity of PCR and NASBA followed by oligochromatography for diagnosis of human African trypanosomiasis in clinical samples from D.R. Congo and Uganda.
- Authors
Matovu, Enock; Mugasa, Claire M; Ekangu, Rosine Ali; Deborggraeve, Stijn; Lubega, George W; Laurent, Thierry; Schoone, Gerard J; Schallig, Henk D; Büscher, Philippe
- Abstract
The polymerase chain reaction (PCR) and nucleic acid sequence-based amplification (NASBA) have been recently modified by coupling to oligochromatography (OC) for easy and fast visualisation of products. In this study we evaluate the sensitivity and specificity of the PCR-OC and NASBA-OC for diagnosis of Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense human African trypanosomiasis (HAT).
- Publication
PLoS neglected tropical diseases, 2010, Vol 4, Issue 7, pe737
- ISSN
1935-2735
- Publication type
Journal Article
- DOI
10.1371/journal.pntd.0000737