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- Title
A meta-analysis of the effectiveness of albendazole compared with metronidazole as treatments for infections with Giardia duodenalis.
- Authors
Solaymani-Mohammadi, Shahram; Genkinger, Jeanine M; Loffredo, Christopher A; Singer, Steven M
- Abstract
Metronidazole is the most commonly used drug for the treatment of giardiasis in humans. In spite of its therapeutic efficacy for giardiasis, low patient compliance, especially in children, side effects, and the emergence of metronidazole-resistant strains may restrict its use. Albendazole has been used to treat Giardia duodenalis infections in recent years. However, efficacy studies in vivo and in vitro have produced diverse results as to its effectiveness. A moderately benign side effect profile, combined with established efficacy against many helminths, renders it promising for treatment of giardiasis in humans.
- Publication
PLoS neglected tropical diseases, 2010, Vol 4, Issue 5, pe682
- ISSN
1935-2735
- Publication type
Journal Article
- DOI
10.1371/journal.pntd.0000682