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- Title
Bacterial vaginosis associated with increased risk of female-to-male HIV-1 transmission: a prospective cohort analysis among African couples.
- Authors
Cohen, Craig R; Lingappa, Jairam R; Baeten, Jared M; Ngayo, Musa O; Spiegel, Carol A; Hong, Ting; Donnell, Deborah; Celum, Connie; Kapiga, Saidi; Delany, Sinead; Bukusi, Elizabeth A
- Abstract
Bacterial vaginosis (BV), a disruption of the normal vaginal flora, has been associated with a 60% increased risk of HIV-1 acquisition in women and higher concentration of HIV-1 RNA in the genital tract of HIV-1-infected women. However, whether BV, which is present in up to half of African HIV-1-infected women, is associated with an increase in HIV-1 transmission to male partners has not been assessed in previous studies.
- Publication
PLoS medicine, 2012, Vol 9, Issue 6, pe1001251
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.1001251