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- Title
The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach.
- Authors
Nordestgaard, Børge G; Palmer, Tom M; Benn, Marianne; Zacho, Jeppe; Tybjaerg-Hansen, Anne; Davey Smith, George; Timpson, Nicholas J
- Abstract
Adiposity, assessed as elevated body mass index (BMI), is associated with increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown. We tested the hypothesis that positive observational associations between BMI and IHD are causal.
- Publication
PLoS medicine, 2012, Vol 9, Issue 5, pe1001212
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.1001212