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- Title
Characterisation of Clostridium difficile hospital ward-based transmission using extensive epidemiological data and molecular typing.
- Authors
Walker, A Sarah; Eyre, David W; Wyllie, David H; Dingle, Kate E; Harding, Rosalind M; O'Connor, Lily; Griffiths, David; Vaughan, Ali; Finney, John; Wilcox, Mark H; Crook, Derrick W; Peto, Tim E A
- Abstract
Clostridium difficile infection (CDI) is a leading cause of antibiotic-associated diarrhoea and is endemic in hospitals, hindering the identification of sources and routes of transmission based on shared time and space alone. This may compromise rational control despite costly prevention strategies. This study aimed to investigate ward-based transmission of C. difficile, by subdividing outbreaks into distinct lineages defined by multi-locus sequence typing (MLST).
- Publication
PLoS medicine, 2012, Vol 9, Issue 2, pe1001172
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.1001172