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- Title
Ensemble modeling of the likely public health impact of a pre-erythrocytic malaria vaccine.
- Authors
Smith, Thomas; Ross, Amanda; Maire, Nicolas; Chitnis, Nakul; Studer, Alain; Hardy, Diggory; Brooks, Alan; Penny, Melissa; Tanner, Marcel
- Abstract
The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (EPI) in areas of stable endemic transmission of Plasmodium falciparum, and have been calibrated for such settings. Their applicability to low transmission settings is unclear. Evaluations of the efficiency of different deployment strategies in diverse settings should consider uncertainties in model structure.
- Publication
PLoS medicine, 2012, Vol 9, Issue 1, pe1001157
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.1001157