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- Title
Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis.
- Authors
Low, Nicola; Chersich, Matthew F; Schmidlin, Kurt; Egger, Matthias; Francis, Suzanna C; van de Wijgert, Janneke H H M; Hayes, Richard J; Baeten, Jared M; Brown, Joelle; Delany-Moretlwe, Sinead; Kaul, Rupert; McGrath, Nuala; Morrison, Charles; Myer, Landon; Temmerman, Marleen; van der Straten, Ariane; Watson-Jones, Deborah; Zwahlen, Marcel; Hilber, Adriane Martin
- Abstract
Identifying modifiable factors that increase women's vulnerability to HIV is a critical step in developing effective female-initiated prevention interventions. The primary objective of this study was to pool individual participant data from prospective longitudinal studies to investigate the association between intravaginal practices and acquisition of HIV infection among women in sub-Saharan Africa. Secondary objectives were to investigate associations between intravaginal practices and disrupted vaginal flora; and between disrupted vaginal flora and HIV acquisition.
- Publication
PLoS medicine, 2011, Vol 8, Issue 2, pe1000416
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.1000416