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- Title
Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: a prospective cohort study.
- Authors
Boulware, David R; Meya, David B; Bergemann, Tracy L; Wiesner, Darin L; Rhein, Joshua; Musubire, Abdu; Lee, Sarah J; Kambugu, Andrew; Janoff, Edward N; Bohjanen, Paul R
- Abstract
Although antiretroviral therapy (ART) improves survival in persons with cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution inflammatory syndrome (IRIS), an exaggerated and frequently deadly inflammatory reaction that complicates recovery from immunodeficiency. The pathogenesis of IRIS is poorly understood and prediction of IRIS is not possible.
- Publication
PLoS medicine, 2010, Vol 7, Issue 12, pe1000384
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.1000384