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- Title
Inflammatory cytokines as risk factors for a first venous thrombosis: a prospective population-based study.
- Authors
Christiansen, Sverre C; Naess, Inger Anne; Cannegieter, Suzanne C; Hammerstrøm, Jens; Rosendaal, Frits R; Reitsma, Pieter H
- Abstract
In case-control studies, elevated levels of interleukins 6 and 8 have been found to be associated with an increased risk of venous thrombosis (VT). Because of the design of these studies, it remained uncertain whether these alterations were a cause or a result of the VT. In order to distinguish between the two, we set out to measure the levels of six inflammatory markers prior to thrombosis in a population-based cohort using a nested case-cohort design.
- Publication
PLoS medicine, 2006, Vol 3, Issue 8, pe334
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.0030334