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- Title
Genome microevolution of chikungunya viruses causing the Indian Ocean outbreak.
- Authors
Schuffenecker, Isabelle; Iteman, Isabelle; Michault, Alain; Murri, Séverine; Frangeul, Lionel; Vaney, Marie-Christine; Lavenir, Rachel; Pardigon, Nathalie; Reynes, Jean-Marc; Pettinelli, François; Biscornet, Leon; Diancourt, Laure; Michel, Stéphanie; Duquerroy, Stéphane; Guigon, Ghislaine; Frenkiel, Marie-Pascale; Bréhin, Anne-Claire; Cubito, Nadège; Desprès, Philippe; Kunst, Frank; Rey, Félix A; Zeller, Hervé; Brisse, Sylvain
- Abstract
A chikungunya virus outbreak of unprecedented magnitude is currently ongoing in Indian Ocean territories. In Réunion Island, this alphavirus has already infected about one-third of the human population. The main clinical symptom of the disease is a painful and invalidating poly-arthralgia. Besides the arthralgic form, 123 patients with a confirmed chikungunya infection have developed severe clinical signs, i.e., neurological signs or fulminant hepatitis.
- Publication
PLoS medicine, 2006, Vol 3, Issue 7, pe263
- ISSN
1549-1676
- Publication type
Journal Article
- DOI
10.1371/journal.pmed.0030263