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Title
Dosage Compensation in the Mouse Balances Up-Regulation and Silencing of X-Linked Genes.
Authors
Hong Lin; Gupta, Vibhor; VerMilyea, Matthew D.; Falciani, Francesco; Lee, Jeannie T.; O'Neill, Laura P.; Turner, Bryan M.
Abstract
In mouse embryonic stem cells, X:autosome expression balance is achieved by up-regulating X-linked genes in both sexes and gene-by-gene silencing on one female X chromosome.