Works matching AU Hoeijmakers, J. H. J.

Results: 122
    1

    Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1<sup>Δ</sup><sup>/−</sup> Mice.

    Published in:
    Aging Cell, 2025, v. 24, n. 7, p. 1, doi. 10.1111/acel.70062
    By:
    • Stefens, S. J. M.;
    • van der Linden, J.;
    • Heredia‐Genestar, J. M.;
    • Brandt, R. M. C.;
    • Barnhoorn, S.;
    • Nieuwenhuizen‐Bakker, I.;
    • van Vliet, N.;
    • Odijk, J. H. M.;
    • Ridwan, Y.;
    • Stuijts, D.;
    • Batenburg, M.;
    • Hoeijmakers, J. H. J.;
    • Kanaar, R.;
    • Essers, J.;
    • van der Pluijm, I.
    Publication type:
    Article
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    Correction: Impaired Genome Maintenance Suppresses the Growth HormoneInsulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.

    Published in:
    2008
    By:
    • van der Pluijm, Ingrid;
    • Garinis, George A.;
    • Brandt, Renata M. C.;
    • Gorgels, Theo G. M. F.;
    • Wijnhoven, Susan W.;
    • Diderich, Karin E. M.;
    • de Wit, Jan;
    • Mitchell, James R.;
    • van Oostrom, Conny;
    • Beems, Rudolf;
    • Niedernhofer, Laura J.;
    • Velasco, Susana;
    • Friedberg, Errol C.;
    • Tanaka, Kiyoji;
    • van Steeg, Harry;
    • Hoeijmakers, Jan H. J.;
    • van der Horst, Gijsbertus T. J.
    Publication type:
    Correction Notice
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    Impaired Genome Maintenance Suppresses the Growth Hormone--Insulin-Like Growth Factor 1 Axis in Mice with Cockayne Syndrome.

    Published in:
    PLoS Biology, 2007, v. 5, n. 1, p. 23, doi. 10.1371/journal.pbio.0050002
    By:
    • van der Pluijm, Ingrid;
    • Garinis, George A.;
    • Brandt, Renata M. C.;
    • Gorgels, Theo G. M. F.;
    • Wijnhoven, Susan W.;
    • Diderich, Karin E. M.;
    • de Wit, Jan;
    • Mitchell, James R.;
    • van Oostrom, Conny;
    • Beems, Rudolf;
    • Niedernhofer, Laura J.;
    • Velasco, Susana;
    • Friedberg, Errol C.;
    • Tanaka, Kiyoji;
    • van Steeg, Harry;
    • Hoeijmakers, Jan H. J.;
    • van der Horst, Gijsbertus T. J.
    Publication type:
    Article
    5

    Rescue of Progeria in Trichothiodystrophy by Homozygous Lethal Xpd Alleles.

    Published in:
    PLoS Biology, 2006, v. 4, n. 10, p. 1821, doi. 10.1371/journal.pbio.0040322
    By:
    • Andressoo, Jaan-Olle;
    • Jans, Judith;
    • de Wit, Jan;
    • Coin, Frederic;
    • Hoogstraten, Deborah;
    • van de Ven, Marieke;
    • Toussaint, Wendy;
    • Huijmans, Jan;
    • Bing Thio, H.;
    • van Leeuwen, Wibeke J.;
    • de Boer, Jan;
    • Egly, Jean-Marc;
    • Hoeijmakers, Jan H. J.;
    • van der Horst, Gijsbertus T. J.;
    • Mitchell, James R.
    Publication type:
    Article
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    The small CRL4<sup>CSA</sup> ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50584-7
    By:
    • Llerena Schiffmacher, Diana A.;
    • Lee, Shun-Hsiao;
    • Kliza, Katarzyna W.;
    • Theil, Arjan F.;
    • Akita, Masaki;
    • Helfricht, Angela;
    • Bezstarosti, Karel;
    • Gonzalo-Hansen, Camila;
    • van Attikum, Haico;
    • Verlaan-de Vries, Matty;
    • Vertegaal, Alfred C. O.;
    • Hoeijmakers, Jan H. J.;
    • Marteijn, Jurgen A.;
    • Lans, Hannes;
    • Demmers, Jeroen A. A.;
    • Vermeulen, Michiel;
    • Sixma, Titia K.;
    • Ogi, Tomoo;
    • Vermeulen, Wim;
    • Pines, Alex
    Publication type:
    Article
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    Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1<sup>Δ/−</sup> mice.

    Published in:
    Clinical Science, 2017, v. 131, n. 15, p. 1941, doi. 10.1042/CS20170026
    By:
    • Haiyan Wu;
    • van Thiel, Bibi S.;
    • Bautista-Niño, Paula K.;
    • Reiling, Erwin;
    • Durik, Matej;
    • Leijten, Frank P. J.;
    • Ridwan, Yanto;
    • Brandt, Renata M.C.;
    • van Steeg, Harry;
    • Dollé, Martijn E. T.;
    • Vermeij, Wilbert P.;
    • Hoeijmakers, Jan H. J.;
    • Essers, Jeroen;
    • van der Pluijm, Ingrid;
    • Danser, A. H. Jan;
    • Roks, Anton J. M.
    Publication type:
    Article
    19

    A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

    Published in:
    Nature, 2006, v. 444, n. 7122, p. 1038, doi. 10.1038/nature05456
    By:
    • Niedernhofer, Laura J.;
    • Garinis, George A.;
    • Raams, Anja;
    • Lalai, Astrid S.;
    • Robinson, Andria Rasile;
    • Appeldoorn, Esther;
    • Odijk, Hanny;
    • Oostendorp, Roos;
    • Ahmad, Anwaar;
    • van Leeuwen, Wibeke;
    • Theil, Arjan F.;
    • Vermeulen, Wim;
    • van der Horst, Gijsbertus T. J.;
    • Meinecke, Peter;
    • Kleijer, Wim J.;
    • Vijg, Jan;
    • Jaspers, Nicolaas G. J.;
    • Hoeijmakers, Jan H. J.
    Publication type:
    Article
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    De novo variants in <italic>CDK13</italic> associated with syndromic ID/DD: Molecular and clinical delineation of 15 individuals and a further review.

    Published in:
    Clinical Genetics, 2018, v. 93, n. 5, p. 1000, doi. 10.1111/cge.13225
    By:
    • van den Akker, W. M. R.;
    • Brummelman, I.;
    • Martis, L. M.;
    • Timmermans, R. N.;
    • Pfundt, R.;
    • Kleefstra, T.;
    • Willemsen, M. H.;
    • de Vries, B. B. A.;
    • Schuurs‐Hoeijmakers, J. H. M.;
    • Gerkes, E. H.;
    • Herkert, J. C.;
    • van Essen, A. J.;
    • Rump, P.;
    • Vansenne, F.;
    • Terhal, P. A.;
    • van Gassen, K. L. I.;
    • van Haelst, M. M.;
    • Cristian, I.;
    • Turner, C. E.;
    • Cho, M. T.
    Publication type:
    Article
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    From a DNA helicase to brittle hair.

    Published in:
    Nature Genetics, 1998, v. 20, n. 2, p. 106, doi. 10.1038/2396
    By:
    • Winkler, G. Sebastiaan;
    • Hoeijmakers, Jan H J
    Publication type:
    Article
    33

    Cell-Autonomous Progeroid Changes in Conditional Mouse Models for Repair Endonuclease XPG Deficiency.

    Published in:
    PLoS Genetics, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.pgen.1004686
    By:
    • Barnhoorn, Sander;
    • Uittenboogaard, Lieneke M.;
    • Jaarsma, Dick;
    • Vermeij, Wilbert P.;
    • Tresini, Maria;
    • Weymaere, Michael;
    • Menoni, Hervé;
    • Brandt, Renata M. C.;
    • de Waard, Monique C.;
    • Botter, Sander M.;
    • Sarker, Altaf H.;
    • Jaspers, Nicolaas G. J.;
    • van der Horst, Gijsbertus T. J.;
    • Cooper, Priscilla K.;
    • Hoeijmakers, Jan H. J.;
    • van der Pluijm, Ingrid
    Publication type:
    Article
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    Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms.

    Published in:
    PLoS Genetics, 2008, v. 4, n. 8, p. 1, doi. 10.1371/journal.pgen.1000161
    By:
    • Schumacher, Björn;
    • van der Pluijm, Ingrid;
    • Moorhouse, Michael J.;
    • Kosteas, Theodore;
    • Robinson, Andria Rasile;
    • Yousin Suh;
    • Breit, Timo M.;
    • van Steeg, Harry;
    • Niedernhofer, Laura J.;
    • van IJcken, Wilfred;
    • Bartke, Andrzej;
    • Spindler, Stephen R.;
    • Hoeijmakers, Jan H. J.;
    • van der Horst, Gijsbertus T. J.;
    • Garinis, George A.
    Publication type:
    Article
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    Metabolomic analysis of dietary‐restriction‐induced attenuation of sarcopenia in prematurely aging DNA repair‐deficient mice.

    Published in:
    Journal of Cachexia, Sarcopenia & Muscle, 2024, v. 15, n. 3, p. 868, doi. 10.1002/jcsm.13433
    By:
    • He, Yupeng;
    • Yang, Wei;
    • Huang, Luojiao;
    • Mever, Marlien Admiraal‐van;
    • Ramautar, Rawi;
    • Harms, Amy;
    • Rijksen, Yvonne;
    • Brandt, Renata M.C.;
    • Barnhoorn, Sander;
    • Smit, Kimberly;
    • Jaarsma, Dick;
    • Lindenburg, Peter;
    • Hoeijmakers, Jan H. J.;
    • Vermeij, Wilbert P.;
    • Hankemeier, Thomas
    Publication type:
    Article
    44

    Protein instability associated with AARS1 and MARS1 mutations causes trichothiodystrophy.

    Published in:
    Human Molecular Genetics, 2021, v. 30, n. 18, p. 1711, doi. 10.1093/hmg/ddab123
    By:
    • Botta, Elena;
    • Theil, Arjan F;
    • Raams, Anja;
    • Caligiuri, Giuseppina;
    • Giachetti, Sarah;
    • Bione, Silvia;
    • Accadia, Maria;
    • Lombardi, Anita;
    • Smith, Desiree E C;
    • Mendes, Marisa I;
    • Swagemakers, Sigrid M A;
    • Spek, Peter J van der;
    • Salomons, Gajja S;
    • Hoeijmakers, Jan H J;
    • Yesodharan, Dhanya;
    • Nampoothiri, Sheela;
    • Ogi, Tomoo;
    • Lehmann, Alan R;
    • Orioli, Donata;
    • Vermeulen, Wim
    Publication type:
    Article
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    The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.

    Published in:
    Frontiers in Aging, 2022, p. 1, doi. 10.3389/fragi.2022.1005322
    By:
    • Birkisdóttir, María B.;
    • van Galen, Ivar;
    • Brandt, Renata M. C.;
    • Barnhoorn, Sander;
    • van Vliet, Nicole;
    • van Dijk, Claire;
    • Nagarajah, Bhawani;
    • Imholz, Sandra;
    • van Oostrom, Conny T.;
    • Reiling, Erwin;
    • Gyenis, Ákos;
    • Mastroberardino, Pier G.;
    • Jaarsma, Dick;
    • van Steeg, Harry;
    • Hoeijmakers, Jan H. J.;
    • Dollé, Martijn E. T.;
    • Vermeij, Wilbert P.
    Publication type:
    Article
    47

    Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice.

    Published in:
    Molecular Imaging & Biology, 2024, v. 26, n. 4, p. 628, doi. 10.1007/s11307-024-01902-4
    By:
    • van Thiel, Bibi S.;
    • de Boer, Martine;
    • Ridwan, Yanto;
    • de Kleijnen, Marion G. J.;
    • van Vliet, Nicole;
    • van der Linden, Janette;
    • de Beer, Isa;
    • van Heijningen, Paula M.;
    • Vermeij, Wilbert P.;
    • Hoeijmakers, Jan H. J.;
    • Danser, A. H. Jan;
    • Kanaar, Roland;
    • Duncker, Dirk J.;
    • van der Pluijm, Ingrid;
    • Essers, Jeroen
    Publication type:
    Article
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