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- Title
E-cadherin is a specific marker for erythroid differentiation and has utility, in combination with CD117 and CD34, for enumerating myeloblasts in hematopoietic neoplasms.
- Authors
Ohgami, Robert S; Chisholm, Karen M; Ma, Lisa; Arber, Daniel A
- Abstract
E-cadherin, epithelial calcium-dependent cell adhesion protein, has been identified as a marker of immature erythroid precursors in recent years. However, the specificity of E-cadherin in bone marrow specimens for erythroblasts vs myeloblasts or other early hematopoietic precursors in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) has not been fully elucidated.
- Publication
American journal of clinical pathology, 2014, Vol 141, Issue 5, p656
- ISSN
1943-7722
- Publication type
Journal Article
- DOI
10.1309/AJCP8M4QQTAZPGRP