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- Title
Long-lasting neural and behavioral effects of iron deficiency in infancy.
- Authors
Lozoff, Betsy; Beard, John; Connor, James; Barbara, Felt; Georgieff, Michael; Schallert, Timothy
- Abstract
Infants are at high risk for iron deficiency and iron-deficiency anemia. This review summarizes evidence of long-term effects of iron deficiency in infancy. Follow-up studies from preschool age to adolescence report poorer cognitive, motor, and social-emotional function, as well as persisting neurophysiologic differences. Research in animal models points to mechanisms for such long-lasting effects. Potential mechanisms relate to effects of iron deficiency during brain development on neurometabolism, myelination, and neurotransmitter function.
- Publication
Nutrition reviews, 2006, Vol 64, Issue 5 Pt 2, pS34
- ISSN
0029-6643
- Publication type
Journal Article
- DOI
10.1301/nr.2006.may.s34-s43