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- Title
Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells.
- Authors
Pacurari, Maricica; Yin, Xuejun J; Zhao, Jinshun; Ding, Ming; Leonard, Steve S; Schwegler-Berry, Diane; Ducatman, Barbara S; Sbarra, Deborah; Hoover, Mark D; Castranova, Vincent; Vallyathan, Val
- Abstract
Single-wall carbon nanotubes (SWCNTs), with their unique physicochemical and mechanical properties, have many potential new applications in medicine and industry. There has been great concern subsequent to preliminary investigations of the toxicity, biopersistence, pathogenicity, and ability of SWCNTs to translocate to subpleural areas. These results compel studies of potential interactions of SWCNTs with mesothelial cells.
- Publication
Environmental health perspectives, 2008, Vol 116, Issue 9, p1211
- ISSN
0091-6765
- Publication type
Journal Article
- DOI
10.1289/ehp.10924