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Title
Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene.
Authors
Koturbash, Igor; Scherhag, Anne; Sorrentino, Jessica; Sexton, Kenneth; Bodnar, Wanda; Tryndyak, Volodymyr; Latendresse, John R; Swenberg, James A; Beland, Frederick A; Pogribny, Igor P; Rusyn, Ivan
Abstract
1,3-Butadiene (BD) is a high-volume industrial chemical and a known human carcinogen. The main mode of BD carcinogenicity is thought to involve formation of genotoxic epoxides.
Publication
Environmental health perspectives, 2011, Vol 119, Issue 5, p635