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- Title
Molecular characterization of methicillin-resistant Staphylococcus aureus isolated from tertiary care hospitals.
- Authors
Asghar, Atif H
- Abstract
Methicillin-resistant S. aureus (MRSA) tends to be resistant to multiple antibiotics. Methicillin resistance is conferred by the acquisition of the mecA gene, which is carried by a mobile genetic element called the staphylococcal cassette chromosome mec (SCCmec). There are five major types of SCCmec elements (I-V). The majority of hospital-acquired MRSA (HA-MRSA) strains carry SCCmec types I, II, or III, whereas community-acquired MRSA (CA-MRSA) strains carry SCCmec types IV or V. In addition, Panton-Valentine Leucocidin (PVL) is a gene encoding a powerful cytotoxin that is strongly associated with CA-MRSA strains. The present study was aimed to identify the types of SCCmec and PVL genes among clinical MRSA isolates.
- Publication
Pakistan journal of medical sciences, 2014, Vol 30, Issue 4, p698
- ISSN
1682-024X
- Publication type
Journal Article
- DOI
10.12669/pjms.304.4946