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- Title
Laparoscopic versus open radical hysterectomy for stage IB2-IIB cervical cancer in the setting of neoadjuvant chemotherapy: a multi-institutional cohort study.
- Authors
Ghezzi, Fabio; Cromi, Antonella; Ditto, Antonino; Vizza, Enrico; Malzoni, Mario; Raspagliesi, Francesco; Uccella, Stefano; Corrado, Giacomo; Cosentino, Francesco; Gotsch, Francesca; Martinelli, Fabio; Franchi, Massimo
- Abstract
Despite the lack of conclusive evidence supporting this treatment modality, neoadjuvant chemotherapy (NACT) prior to radical surgery is a commonly accepted strategy to manage locally advanced cervical cancer. Radical hysterectomy in chemotherapy-treated patients can be technically challenging due to large volume of residual disease, desmoplastic reaction, and loss of normal tissue planes as a result of the cytotoxic treatment. We sought to assess whether surgical outcomes of laparoscopic radical hysterectomy (LRH) and its open counterpart are equivalent in the setting of NACT.
- Publication
Annals of surgical oncology, 2013, Vol 20, Issue 6, p2007
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-012-2777-5