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- Title
High expression of Y-box-binding protein-1 is associated with poor survival in resectable esophageal squamous cell carcinoma.
- Authors
Li, Yong; Wen, Zhe-Sheng; Yang, Hao-Xian; Luo, Rong-Zhen; Zhang, Ying; Zhang, Mei-Fang; Wang, Xin; Jia, Wei-Hua
- Abstract
Y-box-binding protein-1 (YB-1) is a multifunctional protein that regulates gene expression through both transcriptional and translational mechanism. Its expression has been associated with tumor progression and poor prognosis of many cancers. However, its role and clinical significance in resectable esophageal squamous cell carcinoma (ESCC) is still scanty. The purpose of this study was to investigate the prognostic significance of YB-1 expression by immunohistochemistry in a group of patients with ESCC treated with surgical resection.
- Publication
Annals of surgical oncology, 2011, Vol 18, Issue 12, p3370
- ISSN
1534-4681
- Publication type
Journal Article
- DOI
10.1245/s10434-011-1725-0